Laurinterol from Laurencia johnstonii eliminates Naegleria fowleri triggering PCD by inhibition of ATPases
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چکیده
منابع مشابه
Naegleria fowleri meningoencephalitis.
A 7-year-old boy with no prior illness or altered immunity presented to the emergency department with a 36-hour history of fever (103.7°F), emesis, headache, and lethargy. The patient had a history of swimming in a local lake the week before presentation. Physical examination revealed nuchal rigidity. Computed tomography (CT) of the head was normal. A lumbar puncture revealed a cerebrospinal fl...
متن کاملPrimary Amoebic Meningoencephalitis Caused By Naegleria Fowleri
ABBREVIATIONS B103: Brain cell line 103, CDC: Centers for Disease Control and Prevention, CHO: Chinese Hamster Ovary, CMI: Cell mediated immunity, CNS: Central nervous system, CSF: Cerebro-spinal fluid, E6:Vero monkey kidney cell culture, HLF: Human lung fibroblast, HMG: High mobility group protein, HSP70: Heat shock protein 70, IFA: Immunoflurescent assay, ITS: Internal transcribed spacers, kD...
متن کاملFatal primary meningoencephalitis caused by Naegleria fowleri.
Naegleria fowleri is a free living parasite which habitats in fresh water reservoirs. It causes a fatal nervous system infection known as primary amoebic meningoencephalitis by invading through cribriform plate of nose and gaining entry into brain. We report a case of primary amoebic meningoencephalitis caused by Naegleria fowleri in Karachi, Pakistan, in a 42 years old male poultry farm worker...
متن کاملNaegleria Fowleri in Thailand, 2003
Between 1988 and 2003, Naegleria fowleri was studied extensively in Thailand. The distribution of N. fowleri has been studied in many provinces since 1988. During 2001-2003, we received financial support from Mahidol University to study the distribution of pathogenic Naegleria spp in water reservoirs in central, northern, and western parts of Thailand. With these funds, research was conducted i...
متن کاملUltrastructure of Naegleria fowleri enflagellation.
Amoebae of Naegleria fowleri nN68 became elongated flagellated cells 150 to 180 min after subculture to non-nutrient buffer. N. fowleri NF69 did not become elongated or flagellated under these conditions. Electron microscopic examination of N. fowleri confirmed that it is a typical eucaryotic protist with a distinct nuclear envelope and prominent nucleolus, numerous vacuoles and cytoplasmic inc...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2020
ISSN: 2045-2322
DOI: 10.1038/s41598-020-74729-y